CBD is very adaptable and is available in a variety of forms. Despite the benefits and drawbacks of each product, the majority of CBD products only let a small amount of the active component into your bloodstream.
The amount of CBD that is currently available for use in your body is said to be up to 10 times greater thanks to certain brands Water Soluble CBD, which they claim is the solution to this issue. Unfortunately, there isn't much publicly available evidence to support these assertions because it's so new.
What is CBD that is water soluble?
A more recent technique for incorporating CBD extract into water is to make it water soluble. Cannabinoids are inherently fat-soluble, which implies that they mix poorly with water but dissolve quickly in fatty materials like oils.
Because of this, most CBD products are made of oil. The drawback of CBD derived from oil is that most fats are broken down by enzymes and take longer to enter your bloodstream through your gut.
A certain kind of sound wave can cause CBD to vibrate apart into small, microscopic nanoparticles, as CBD firms have now discovered. Adding high pressure emulsifying agents or encasing the cannabis in other tiny materials can likewise produce the same result.
After being broken up into tiny bits, the CBD can mix with water-based solutions because water molecules can fit in between them.
How does it function?
If you take CBD oil, it must first be broken down into tiny bits in order for it to be used by your body tissues. The first pass effect, which refers to the processes that cause this breakdown, is what causes oral CBD oil to have a low bioavailability.
The first pass effect happens in your intestines and then moves on to your liver in two phases. Bile and pancreatic secretions from your gall bladder and pancreas enter your gut during the first stage. They have enzymes that break down fats and CBD, which is fat-soluble, into tiny pieces so they can cross your gut wall and go into your blood. The second stage involves your blood passing the tiny fragments through your liver, which further breaks them down.
The initial stage of the first pass effect is intended to be missed by CBD Water Soluble. It can enter your blood without having to first undergo digestion in your gut. Once in the bloodstream, it must then go to the liver where, like all other consumed substances, it is broken down.
Both CBD oil and Water Soluble CBD must be metabolized by the liver, but since water-soluble products skip the initial 'gut' stage of the first pass effect, it's possible that more of the active ingredient will be retained after passing through the liver in water-soluble goods.
Does CBD that is water soluble absorb more readily under the tongue?
Lipase is the primary enzyme in charge of breaking down lipids during the first pass effect. You can find it in your mouth, gallbladder, and, strangely, in your digestive system. Lingual lipase, which is present when you hold CBD oil under your tongue, breaks it down so that it can enter your sublingual blood vessels.
CBD Water Soluble is already in a state that can pass through the membrane and into your blood when you place it under your tongue. Therefore, the lipase does not need to break it down, just like in your stomach. A benefit of allowing Water Soluble CBD soak beneath your tongue is that more cannabinoids may reach your cells because it won't need to pass through your liver.
Does Water Soluble CBD indicate that more gets into your blood?
The claims of increased bioavailability may be based on research done in 2017 at the Hebrew University of Jerusalem, where researchers examined how well THC and CBD found in nano-spheres were absorbed. The cannabinoids were carefully packaged in molecular packets and allowed to dissolve in water during the investigation, which involved rats.
The amount that was available for usage in cells increased astonishingly by 600%, according to the findings. This demonstrates the amazing potential of Water Soluble CBD, but regrettably it does not imply that all CBD Water Soluble products will function in the same way. Despite the fact that there are numerous water soluble and nano CBD product varieties available, each one is made in a unique manner to a unique set of standards and has a unique set of outcomes.
The success of the nano-spheres, according to this study's findings, was due to their ability to keep the active ingredient enclosed until after it had gone through the gut wall. They then start to disintegrate and disclose their contents. The outcomes will be very different if the CBD de-emulsifies or exits its nano-sphere too soon or too late.
As a result, water-soluble compounds are probably a good approach to boost the absorption of cannabis, but further research is required to fully understand the mechanisms at play. How effectively it works depends on how quickly the CBD transforms back into its fat-soluble state after being made water soluble.
What are the benefits of CBD that is soluble in water?
A CBD product can benefit greatly from its water solubility. It can be included in water-based products, allowing manufacturers to incorporate it into foods and beverages without also including oil.
It doesn't produce big oily drips when used in pumps and sprays. It is much simpler to take Water Soluble CBD.
It enters your bloodstream immediately.
It's likely that more CBD will enter your bloodstream.
It can be included in water-based dishes and beverages.
It is simpler to add flavors that are water soluble to it.
It works better when applied in a spray or pump bottle.
It provides more alternatives to consume it.
It's unclear how much the effect will be stronger and if this is true for everyone once CBD is in your blood.
Different water-soluble and nanoformulations of CBD exist. Some might work better than others.
A great stride toward the future for cannabinoids and other comparable chemicals is CBD Water Soluble. This technology is already used by certain products to increase their effectiveness and usability. The most efficient ways to generate these products and the precise behavior of nanoparticles after they have penetrated the gut wall are still unknown.